locus-to-gene-mapper-skill
Map GWAS loci to ranked candidate genes using a deterministic multi-skill chain (EFO - GWAS - coordinates - Open Targets L2G/coloc - eQTL - burden/coding context), with reproducible tables and optional figures. Use when a user provides a trait/EFO term and/or lead variants and needs locus-to-gene prioritization for dow Published by openai in plugins.
What is locus-to-gene-mapper-skill?
Map GWAS loci to ranked candidate genes using a deterministic multi-skill chain (EFO - GWAS - coordinates - Open Targets L2G/coloc - eQTL - burden/coding context), with reproducible tables and optional figures. Use when a user provides a trait/EFO term and/or lead variants and needs locus-to-gene prioritization for dow Published by openai in plugins. This profile combines repository metadata with install, compatibility, and usage signals so developers can quickly decide whether it fits their agent workflow before opening the source repository.
Automated repository signals based on public metadata such as recency, license, installation evidence, and adoption. These are not a security audit or endorsement.
Key capabilities
- Includes SKILL.md support
- Reusable instructions support
- Developers using plugins
Technical details
- Install or run with Copy skill directory
When to use locus-to-gene-mapper-skill
- Use it for developers using plugins.
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Editorial notes
Source
- Creator: openai
- Repository: openai/plugins
- Skill file: plugins/life-science-research/skills/locus-to-gene-mapper-skill/SKILL.md
What it does
Map GWAS loci to ranked candidate genes using a deterministic multi-skill chain (EFO - GWAS - coordinates - Open Targets L2G/coloc - eQTL - burden/coding context), with reproducible tables and optional figures. Use when a user provides a trait/EFO term and/or lead variants and needs locus-to-gene prioritization for dow
Skill instructions
Locus-to-Gene Mapper Generate a reproducible locus-to-gene mapping for one trait (or a seed set of lead variants), with explicit evidence attribution and conservative confidence labels. This skill is optimized for bioinformaticians who need executable, traceable mapping from variant signals to plausible causal genes. Required Inputs Provide at least one anchor source: - traitquery (string), for example chronic obstructive pulmonary disease - efoid (string), for example EFO0000341 - seedrsids (list[string]), for example ["rs1873625", "rs7903146"] Optional Inputs - targetgene (string), optional gene of interest for highlighting in output - showchildtraits (bool), default true - phenotypeterms (list[string]), optional additional terms to include when finding anchors - maxanchorassociations (int), default 1200 - maxloci (int), default 25 - maxgenesperlocus (int), default 10 - maxcolocrowsperlocus (int), default 100 - maxeqtlrowspervariant (int), default 200 - genebassburdensets (list[strin
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Frequently asked questions
What is locus-to-gene-mapper-skill?
locus-to-gene-mapper-skill is a open-source AI agent skill with Copy skill directory. Map GWAS loci to ranked candidate genes using a deterministic multi-skill chain (EFO - GWAS - coordinates - Open Targets L2G/coloc - eQTL - burden/coding context), with reproducible tables and.
Who is locus-to-gene-mapper-skill best for?
locus-to-gene-mapper-skill is best for reusing agent instructions, scripts, and references.
How do I install locus-to-gene-mapper-skill?
Install or run locus-to-gene-mapper-skill using Copy skill directory. Check locus-to-gene-mapper-skill for the latest setup command.
Is locus-to-gene-mapper-skill actively maintained?
locus-to-gene-mapper-skill may need a closer maintenance check before production use.
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