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boltz-small-molecule-design Skill

AI Agent SkillDesign & MediaJavaScriptOpen source

Design new small-molecule binders with Boltz. Use when generating novel ligands or hits for a target without a fixed compound library. Not for screening existing molecules or one-off docking. Published by openai in plugins.

Decision snapshot

Is this a fit?

Best for

Browser automation, Design and media, Includes SKILL.md, Reusable instructions

Works with

Compatibility not yet detected.

Access

Permission behavior not yet detected.

Setup

Copy skill directory

Project health

19 days ago

Considerations

No specific cautions were detected. Review the source and requested permissions before installing.

What is boltz-small-molecule-design Skill?

Design new small-molecule binders with Boltz. Use when generating novel ligands or hits for a target without a fixed compound library. Not for screening existing molecules or one-off docking. Published by openai in plugins. This profile combines repository metadata with install, compatibility, and usage signals so developers can quickly decide whether it fits their agent workflow before opening the source repository.

Trust signal
95/100
Maintenance signal
90/100
Adoption signal
92/100

Automated repository signals based on public metadata such as recency, license, installation evidence, and adoption. These are not a security audit or endorsement. See how SkillIndex evaluates profiles.

Key capabilities

  • Includes SKILL.md support
  • Reusable instructions support
  • Browser automation
  • Design and media
  • Browser automation use cases
  • Design and media use cases

Declared skill metadata

  • Source file: plugins/boltz-api-cli/skills/boltz-small-molecule-design/SKILL.md

These fields retain source and confidence evidence from the indexed SKILL.md.

Compatibility and setup

Copy skill directory
  • Install or run with Copy skill directory

When to use boltz-small-molecule-design Skill

  • Use it for browser automation.
  • Use it for design and media.

Built with

JavaScriptCopy skill directory

Editorial notes

Source

  • Creator: openai
  • Repository: openai/plugins
  • Skill file: plugins/boltz-api-cli/skills/boltz-small-molecule-design/SKILL.md

What it does

Design new small-molecule binders with Boltz. Use when generating novel ligands or hits for a target without a fixed compound library. Not for screening existing molecules or one-off docking.

Skill instructions

Workflow If boltz-api is missing from PATH, use boltz-cli-setup for install/update guidance before retrying. If a command reports missing or expired authentication, use boltz-cli-setup to start boltz-api auth login --device-code before retrying; do not ask permission first. If the agent host sandbox blocks boltz-api install/auth/API calls, use boltz-cli-setup to request the host sandbox bypass/escalation needed for user-wide CLI install, browser login, credential storage, temp files, or API access before retrying. Use this skill when the user wants de novo small-molecule binders (no existing library). 1. Normalize the target: one or more protein sequences into target.entities, plus optional pocketresidues (0-based) and/or referenceligands (known binders to help locate the pocket). 2. Pick nummolecules — valid range 10 to 1,000,000 (server rejects outside it). If the user says fewer than 10, explain the floor and propose 10. 3. Only add chemicalspace (e.g. "enaminereal") if the user exp

Verified compatibility and discovery

Frequently asked questions

What is boltz-small-molecule-design?

boltz-small-molecule-design is a open-source AI agent skill with Copy skill directory. Design new small-molecule binders with Boltz. Use when generating novel ligands or hits for a target without a fixed compound library. Not for screening existing molecules or one-off docking.

Who is boltz-small-molecule-design best for?

boltz-small-molecule-design is best for reusing agent instructions, scripts, and references, browser automation workflows, design and media workflows.

How do I install boltz-small-molecule-design?

Install or run boltz-small-molecule-design using Copy skill directory. Check boltz-small-molecule-design for the latest setup command.

Is boltz-small-molecule-design actively maintained?

boltz-small-molecule-design may need a closer maintenance check before production use.

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Stars
5,140
Forks
717
Last commit
19 days ago
Last verified
Aug 25, 2026
Metadata fetched
Aug 25, 2026
Repository age
6 months
License
Unknown

Project health auto-fetched from the source repository.

Maintain this resource?

Review this source-backed profile, send a correction with evidence, or link to it from your documentation. Claims verify your relationship to the project; profile facts still require source evidence and editorial review.

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